The
Malaysian Journal of Analytical Sciences Vol 15 No 1 (2011): 22 – 26
ISOLATION OF CHEMICAL CONSTITUENTS FROM RHIZOMES OF ETLINGERA
SPHAEROCEPHALA VAR. GRANDIFLORA
M.A.A. Yahya1,
W.A. Yaacob1* and
1School of Chemical Sciences and Food Technology,
2School of Bioscience and Biotechnology,
Faculty
of Science and Technology, Universiti Kebangsaan Malaysia,
43600
Bangi, Selangor, Malaysia.
*Corresponding author: wanyaa@ukm.my
Abstract
A phytochemical investigation was conducted on the rhizomes of Etlingera
sphaerocephala var. grandiflora (Zingiberaceae).
Steroids of β-sitosterol
and stigmasterol, together with a phenolic compound of paeonol were isolated
using several chromatographic means. Their structures were established on the
basis of extensive spectroscopic (IR, MS, NMR) data analysis and by comparison
of the data obtained with those of the literature.
Keywords: Zingiberaceae, Etlingera
sphaerocephala
var. grandiflora, β-sitosterol, stigmasterol, paeonol, NMR
References
1.
Turner,
I.M. (1995). A catalogue of the vascular plants of Malaya. Gardens’ Bulletin Singapore.
47(2): 642-655.
2.
Lim,
C.K. (2001). Taxonomic notes on Etlingera
Giseke (Zingiberaceae) in Peninsular Malaysia: the “Achasma”
taxa and supplementary notes on the “Nicolaia”
taxa. Folia Malaysiana. 2(3): 141-178, 209-210.
3.
Poulsen,
A.D. (2006). Etlingera of Borneo. Natural History Publications (Borneo). Kota
Kinabalu.
4.
Holttum,
R.E. (1950). The Zingiberaceae of the Malay Peninsula. Gardens’ Bulletin Singapore. 13(1):
1-249.
5. Smith, R.M.
(1986). New combinations in Etlingera Giseke (Zingiberaceae). Notes
Royal Botanic Garden Edinburgh. 43: 243-254.
6.
Hussain,
M.M., Rahman, M.S., Jabbar, A., Rashid, M.A. (2008). Phytochemical and
biological investigations of Albizzia lebbeck Benth. Boletín
Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas. 7(5):
273-278.
7.
Zhang, X., Geoffroy, P., Miesch, M., Julien-David, D., Raul, F.,
Aoude-Werner, D., Marchioni, E. (2005). Gram-scale chromatographic purification
of β-sitosterol. Synthesis and characterization of
β-sitosterol oxides. Steroids.
70(13): 886-895.
8.
De-Eknamkul,
W., Potduang, B. (2003). Biosynthesis of β-sitosterol and
stigmasterol in Croton sublyratus proceeds via a mixed origin of
isoprene units. Phytochemistry. 62: 389-398.
9. Peng, W., Zhang, Y., Yang, K., Xiao, Y. (2007).
Chemical constituents of Zingiber
officinale (Zingiberaceae). Yunnan Zhiwu Yanjiu. 29(1): 125-128.
10. Phan, M.G., Le, H.T., Phan, T.S., Otsuka, H. (2007).
Chemical constituents of the fruits of Alpinia
conchigera Griff. (Zingiberaceae). Tap
Chi Hoa Hoc. 45(4):
509-512.
11. Qiao, C., Xu, L., Shen, Y., Hao, X. (1999). Chemical
constituents from Globba racemosa Smith. Huaxue
Yanjiu Yu Yingyong. 11(5):
575-576.
12. Sukari, M.A., Neoh, B.K., Lajis, N.H., Ee, G.C.L.,
Rahmani, M., Ahmad, F.B.H., Yusof, U.K. (2004). Chemical constituents of Kaempferia angustifolia (Zingiberaceae).
Oriental Journal of Chemistry. 20(3): 451-456.
13. Qiao, C., Li, Q., Dong, H., Xu, L., Wang, Z. (2002).
Studies on chemical constituents of two plants from Costus. Zhongguo Zhongyao
Zazhi. 27(2): 123-125.
14. Lognay, G., Marlier, M., Haubruge, E., Trevejo, E.,
Severin, M. (1989). Study of the lipids from Renealmia alpinia (Rott) Maas. Grasas
y Aceites. 40(6): 351-355.
15. Vidari, G., Vita Finzi, P., De Bernardi, M. (1971). Flavonols and quinones in stems of Aframomum giganteum. Phytochemistry. 10(12): 3335-3339.
16. Xiao, P., Sun, C., Zahid, M., Ishrud, O., Pan, Y.
(2001). New diterpene from Hedychium
villosum. Fitoterapia. 72(7): 837-838.
17. Phan, M.G.,
Phan, T.S. (2004). Phytochemical investigation of Alpinia globosa
(Lour.) Horaninov, Zingiberaceae. Tap Chi Hoa Hoc. 42(3): 376-378.
18. Phan, M.G.,
Dang, B.T., Phan, T.S. (2005). Flavonoid compounds from the rhizomes of Alpinia
conchigera Griff., Zingiberaceae. Tap Chi Hoa Hoc. 43(1): 105-108.
19. Kim, M.Y., Lee, H.S., Bae,
K.H., Yun, Y.S., Song, J.Y., Han, Y.S. (2006). Use of paeonol for inhibiting
angiogenesis or for enhancing radiosensitization. PCT Int. Appl. WO 2006121263
A1 20061116.
20. Zhou, F., Tan, G., Liang, P. (1981). Isolation of paeonol, an analgesic
principle from Luculia
intermedia Hutch. Zhongcaoyao. 12(7): 6.
21. Cheng, W., Chen, H., Zhang, Y., Gao, S., Tao, Y., Gu, K.
(2005). Study on chemical constituents in Rosmarinus
officinalis. Zhongcaoyao. 36(11): 1622-1624.
22. Kitagawa, I., Yoshikawa, M., Tsunaga, K., Tani, T. (1979). Studies on Moutan cortex.
ΙΙ. On the chemical constituents. Shoyakugaku
Zasshi. 33(3): 171-177.
23. Ducki, S., Hadfield, J.A., Lawrence, N.J., Zang, X., McGown, A.T. (1995).
Isolation of paeonol from Arisaema
erubescens. Planta Medica. 61(6): 586-587.
24. Matsumoto, M. (1994). 2'-Hydroxy-4'-methoxyacetophenone (paeonol) in Exacum
affine cv. Bioscience,
Biotechnology, and Biochemistry. 58(10):
1892-1893.
25. Weeks, R.A., Dobberstein, R.H., Farnsworth, N.R. (1977). Isolation of
paeonol from Bathysa
meridionalis. Lloydia. 40(5): 515-516.